OBJECTIVES: Strategic planning for coronavirus disease (COVID-19) care has dominated the agenda of medical services, which have been further restricted by the need for minimizing viral transmission. Risk is particularly relevant in relation to endoscopy procedures. This study aimed to describe a contingency plan for a tertiary academic cancer center, define a strategy to prioritize and postpone examinations, and evaluate the infection rate among healthcare workers (HCWs) in the endoscopy unit of the Cancer Institute of the State of São Paulo (ICESP). METHODS: We created a strategy to balance the risk of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and to mitigate the effects of postponing endoscopic procedures in oncological patients. A retrospective analysis of prospectively collected data on all endoscopies between March and June 2020 compared with those during the same period in 2019 was carried out. All HCWs were interviewed to obtain clinical data and SARS-CoV-2 test results. RESULTS: During the COVID-19 outbreak, there was a reduction of 55% in endoscopy cases in total. Colonoscopy was the most affected modality. The total infection rate among all HCWs was 38%. None of the senior digestive endoscopists had COVID-19. However, all bronchoscopists had been infected. One of three fellows had a serological diagnosis of COVID-19. Two-thirds of all nurses were infected, whereas half of all technicians were infected. CONCLUSIONS: In this pandemic scenario, all endoscopy services must prioritize the procedures that will be performed. It was possible to maintain some endoscopic procedures, including those meant to provide nutritional access, tissue diagnosis, and endoscopic resection. Personal protective equipment (PPE) seems effective in preventing transmission of COVID-19 from patients to digestive endoscopists. These measures can be useful in planning, even for pandemics in the future.

Ratos Wistar machos foram expostos por via oral, durante 28 dias, a 1/10 do valor da DL50 (concentração letal) da permetrina (PMT) ou deltametrina (DMT). O objetivo deste estudo foi determinar os resíduos de PMT e DMT no fígado e coração dos ratos ao final do período de exposição e avaliar o efeito nos níveis de resíduos devido à ingestão de pectina e celulose na dieta. Os analitos foram extraídos em acetonitrila e a limpeza dos extratos foi realizada por extração em fase sólida com florisil antes da análise por GC-ECD (cromatografia gasosa com captura de elétrons). Para PMT, os limites de quantificação (LOQ) foram 1,0 e 0,2 µg g-1 e para DMT 0,9 e 0,2 µg g-1 para fígado e coração, respectivamente. Não foi verificada a presença de resíduos de PMT ou DMT acima do LOQ do método, tanto no fígado como no coração dos animais expostos

For 28 days male Wistar rats were submitted to oral exposure with 1/10 of the LD50 value of permethrin (PMT) or deltamethrin (DMT). The aim of this study was to determine the residues of PMT and DMT in the liver and heart of the rats at the end of the exposure period, as well as to evaluate the effect of ingesting pectin and cellulose via the diet. The analytes were extracted with acetonitrile and the extracts were cleaned up by solid phase extraction with florisil before GC-ECD (gas chromatography coupled with an electron-capture detector) analysis. For PMT, the limits of quantitation (LOQ) were 1.0 and 0.2 µg g-1 and for DMT 0.9 and 0.2 µg g-1 for liver and heart, respectively. No PMT or DMT residues were verified above the LOQ of the method in either the liver or heart of the exposed animals

Este trabalho avaliou a eficácia do armazenamento de dejetos de suínos por 120 dias, em três esterqueiras de propriedades suinícolas localizadas na bacia do lajeado Suruvi, município de Concórdia, região oeste de Santa Catarina. Os parâmetros analisados foram: decomposição do material carbonáceo, transformação de compostos nitrogenados, adsorção do fósforo e viabilidade de microrganismos patogênicos. Os resultados revelaram que: a) as maiores remoções de material carbonáceo ocorrem entre 30 e 60 dias de armazenamento; b) o ambiente anaeróbio das esterqueiras impossibilitou as remoções de nitrogênio amoniacal por nitrificação/desnitrificação; c) embora as remoções de ortofosfato na fase líquida do dejeto tenham sido significativas, a estocagem por longo período parece favorecer a migração desse elemento para a fase sólida do resíduo, e d) ao longo dos 120 dias de armazenagem, não foi possível reduzir o NMP médio de coliformes (CF e CT), porém os valores remanescentes ainda são elevados, fato que dificulta a disposição do material.

This work evaluated the effectiveness of the storage of pig slurry during 120 days. It was analyzed the decomposition of the organic material, the transformation of nitrogen compound, the phosphorus adsorption and the viability of pathogenic microorganisms in lagoons from three pig breeding farms located at Lajeado Suruvi basin in Concordia - West of Santa Catarina State, Brazil. The results showed that the largest removals of organic material happened between 30 and 60 days of storage. In the anaerobic lagoon was not possible to remove nitrogen by nitrification/ denitrification. During the liquid phase was possible to remove orthophosphate but when the orthophosphate was storaged for a long period it seemed it was transferred for the solid phase of the residue. During 120 days of storage it was not possible to reduce total and fecal coliforms MPN; however the remaining values are still high.